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The RhoA/Rho kinase pathway regulates nuclear localization of serum response factor.
Liu HW, Halayko AJ, Fernandes DJ, Harmon GS, McCauley JA, Kocieniewski P, McConville J, Fu Y, Forsythe SM, Kogut P, Bellam S, Dowell M, Churchill J, Lesso H, Kassiri K, Mitchell RW, Hershenson MB, Camoretti-Mercado B, Solway J
American journal of respiratory cell and molecular biology. 2003;29(1):39-47.
PMID: 12600823
Actin dynamics: a potential integrator of smooth muscle (Dys-)function and contractile apparatus gene expression in asthma. Parker B. Francis lecture.
Solway J, Bellam S, Dowell M, Camoretti-Mercado B, Dulin N, Fernandes D, Halayko A, Kocieniewski P, Kogut P, Lakser O, Liu HW, McCauley J, McConville J, Mitchell R
Chest. 2003;123(3 Suppl):392S-8S.
PMID: 12629000
What evidence implicates airway smooth muscle in the cause of BHR?
Dulin NO, Fernandes DJ, Dowell M, Bellam S, McConville J, Lakser O, Mitchell R, Camoretti-Mercado B, Kogut P, Solway J
Clinical reviews in allergy & immunology. 2003;24(1):73-84.
PMID: 12644719
The intrinsic apoptotic pathway is required for lipopolysaccharide-induced lung endothelial cell death.
Wang HL, Akinci IO, Baker CM, Urich D, Bellmeyer A, Jain M, Chandel NS, Mutlu GM, Budinger GR
Journal of immunology (Baltimore, Md. : 1950). 2007;179(3):1834-41.
PMID: 17641050
The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production.
Bell EL, Klimova TA, Eisenbart J, Moraes CT, Murphy MP, Budinger GR, Chandel NS
The Journal of cell biology. 2007.
PMID: 17562787
Hypoxic conformance of metabolism in primary rat hepatocytes: a model of hepatic hibernation.
Subramanian RM, Chandel N, Budinger GR, Schumacker PT
Hepatology (Baltimore, Md.). 2007;45(2):455-64.
PMID: 17366663
The cellular basis for diverse responses to oxygen.
Chandel NS, Budinger GR
Free radical biology & medicine. 2007;42(2):165-74.
PMID: 17189822
Hypoxic conformance of metabolism in primary rat hepatocytes: A model of hepatic hibernation.
Subramanian RM, Chandel N, Budinger GR, Schumacker PT
Hepatology (Baltimore, Md.). 2007.
PMID: 17206654
Bronchoalveolar lavage fluid from patients with acute lung injury/acute respiratory distress syndrome induces myofibroblast differentiation.
Synenki L, Chandel NS, Budinger GR, Donnelly HK, Topin J, Eisenbart J, Jovanovic B, Jain M
Critical care medicine. 2007.
PMID: 17255860
p53 mediates particulate matter-induced alveolar epithelial cell mitochondria-regulated apoptosis.
Soberanes S, Panduri V, Mutlu GM, Ghio A, Bundinger GR, Kamp DW
American journal of respiratory and critical care medicine. 2006 Dec;174(11):1229-38.
PMID: 16946128
Leptin Resistance Protects Mice from Hyperoxia-Induced Acute Lung Injury.
Bellmeyer A, Martino JM, Chandel NS, Budinger GS, Dean DA, Mutlu GM
American journal of respiratory and critical care medicine. 2006 Dec.
PMID: 17185651
Air pollution impairs lung's ability to clear edema fluid.
Mutlu GM, Bellmeyer A, Budinger GR
The American journal of cardiology. 2006;98(3):423-4.
PMID: 16860038
Beta-adrenergic receptor stimulation and adenoviral overexpression of superoxide dismutase prevent the hypoxia-mediated decrease in Na,K-ATPase and alveolar fluid reabsorption.
Litvan J, Briva A, Wilson MS, Budinger GR, Sznajder JI, Ridge KM
The Journal of biological chemistry. 2006;281(29):19892-8.
PMID: 16636055
Airborne particulate matter inhibits alveolar fluid reabsorption in mice via oxidant generation.
Mutlu GM, Snyder C, Bellmeyer A, Wang H, Hawkins K, Soberanes S, Welch LC, Ghio AJ, Chandel NS, Kamp D, Sznajder JI, Budinger GR
American journal of respiratory cell and molecular biology. 2006;34(6):670-6.
PMID: 16439801
Hypoxia-mediated degradation of Na,K-ATPase via mitochondrial reactive oxygen species and the ubiquitin-conjugating system.
Comellas AP, Dada LA, Lecuona E, Pesce LM, Chandel NS, Quesada N, Budinger GR, Strous GJ, Ciechanover A, Sznajder JI
Circulation research. 2006;98(10):1314-22.
PMID: 16614303
Proapoptotic Bid is required for pulmonary fibrosis.
Budinger GR, Mutlu GM, Eisenbart J, Fuller AC, Bellmeyer AA, Baker CM, Wilson M, Ridge K, Barrett TA, Lee VY, Chandel NS
Proceedings of the National Academy of Sciences of the United States of America. 2006;103(12):4604-9.
PMID: 16537427
Phosphoinositide-3-kinase gamma: is it really pivotal for ventilator-induced lung injury?
Akinci OI, Budinger GR
Critical care medicine. 2006;34(1):251-2.
PMID: 16374191
Incidence and outcomes of acute lung injury.
Mutlu GM, Budinger GR
The New England journal of medicine. 2006;354(4):416-7; author reply 416-7.
PMID: 16436776
The alveolar-epithelial barrier: a target for potential therapy.
Budinger GR, Sznajder JI
Clinics in chest medicine. 2006;27(4):655-69; abstract ix.
PMID: 17085253
Bleomycin induces alveolar epithelial cell death through JNK-dependent activation of the mitochondrial death pathway.
Lee VY, Schroedl C, Brunelle JK, Buccellato LJ, Akinci OI, Kaneto H, Snyder C, Eisenbart J, Budinger GR, Chandel NS
American journal of physiology. Lung cellular and molecular physiology. 2005 Oct;289(4):L521-8.
PMID: 16148050
Potassium sorbate reduces gastric colonization in patients receiving mechanical ventilation.
Tulaimat A, Laghi F, Mikrut K, Carey RB, Budinger GR
Journal of critical care. 2005;20(3):281-7.
PMID: 16253799
Laminin-6 assembles into multimolecular fibrillar complexes with perlecan and participates in mechanical-signal transduction via a dystroglycan-dependent, integrin-independent mechanism.
Jones JC, Lane K, Hopkinson SB, Lecuona E, Geiger RC, Dean DA, Correa-Meyer E, Gonzales M, Campbell K, Sznajder JI, Budinger S
Journal of cell science. 2005;118(Pt 12):2557-66.
PMID: 15928048
To live or die: a critical decision for the lung.
Budinger GR, Sznajder JI
The Journal of clinical investigation. 2005;115(4):828-30.
PMID: 15841170
Gene transfer of the Na+,K+-ATPase beta1 subunit using electroporation increases lung liquid clearance.
Machado-Aranda D, Adir Y, Young JL, Briva A, Budinger GR, Yeldandi AV, Sznajder JI, Dean DA
American journal of respiratory and critical care medicine. 2005;171(3):204-11.
PMID: 15516538
Active transforming growth factor-beta1 activates the procollagen I promoter in patients with acute lung injury.
Budinger GR, Chandel NS, Donnelly HK, Eisenbart J, Oberoi M, Jain M
Intensive care medicine. 2005;31(1):121-8.
PMID: 15565360
Reactive oxygen species are required for hyperoxia-induced Bax activation and cell death in alveolar epithelial cells.
Buccellato LJ, Tso M, Akinci OI, Chandel NS, Budinger GR
The Journal of biological chemistry. 2004;279(8):6753-60.
PMID: 14625274
c-Myc sensitization to oxygen deprivation-induced cell death is dependent on Bax/Bak, but is independent of p53 and hypoxia-inducible factor-1.
Brunelle JK, Santore MT, Budinger GR, Tang Y, Barrett TA, Zong WX, Kandel E, Keith B, Simon MC, Thompson CB, Hay N, Chandel NS
The Journal of biological chemistry. 2004;279(6):4305-12.
PMID: 14627695
Nitric oxide during ischemia attenuates oxidant stress and cell death during ischemia and reperfusion in cardiomyocytes.
Iwase H, Robin E, Guzy RD, Mungai PT, Vanden Hoek TL, Chandel NS, Levraut J, Schumacker PT
Free radical biology & medicine. 2007;43(4):590-9.
PMID: 17640569
The intrinsic apoptotic pathway is required for lipopolysaccharide-induced lung endothelial cell death.
Wang HL, Akinci IO, Baker CM, Urich D, Bellmeyer A, Jain M, Chandel NS, Mutlu GM, Budinger GR
Journal of immunology (Baltimore, Md. : 1950). 2007;179(3):1834-41.
PMID: 17641050
BCL-2 Family Members Regulate Anoxia-Induced Cell Death.
Shroff EH, Snyder C, Chandel NS
Antioxidants & redox signaling. 2007.
PMID: 17627475
The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production.
Bell EL, Klimova TA, Eisenbart J, Moraes CT, Murphy MP, Budinger GR, Chandel NS
The Journal of cell biology. 2007.
PMID: 17562787
Mitochondrial ROS trigger HIF-dependent extension of replicative lifespan during hypoxia.
Bell EL, Klimova TA, Eisenbart J, Schumacker PT, Chandel NS
Molecular and cellular biology. 2007.
PMID: 17562866
Role of Bcl-2 Family Members in Anoxia Induced Cell Death.
Shroff EH, Snyder C, Chandel NS
Cell cycle (Georgetown, Tex.). 2007;6(7).
PMID: 17377500
Hypoxic conformance of metabolism in primary rat hepatocytes: a model of hepatic hibernation.
Subramanian RM, Chandel N, Budinger GR, Schumacker PT
Hepatology (Baltimore, Md.). 2007;45(2):455-64.
PMID: 17366663
The cellular basis for diverse responses to oxygen.
Chandel NS, Budinger GR
Free radical biology & medicine. 2007;42(2):165-74.
PMID: 17189822
Bronchoalveolar lavage fluid from patients with acute lung injury/acute respiratory distress syndrome induces myofibroblast differentiation.
Synenki L, Chandel NS, Budinger GR, Donnelly HK, Topin J, Eisenbart J, Jovanovic B, Jain M
Critical care medicine. 2007.
PMID: 17255860
Mitochondrial oxygen sensing: regulation of hypoxia-inducible factor by mitochondrial generated reactive oxygen species.
Bell EL, Chandel NS
Essays in biochemistry. 2007;43:17-28.
PMID: 17705790
Loss of Mcl-1 protein and inhibition of electron transport chain together induce anoxic cell death.
Brunelle JK, Shroff EH, Perlman H, Strasser A, Moraes CT, Flavell RA, Danial NN, Keith B, Thompson CB, Chandel NS
Molecular and cellular biology. 2006 Dec.
PMID: 17145774
Leptin Resistance Protects Mice from Hyperoxia-Induced Acute Lung Injury.
Bellmeyer A, Martino JM, Chandel NS, Budinger GS, Dean DA, Mutlu GM
American journal of respiratory and critical care medicine. 2006 Dec.
PMID: 17185651
Airborne particulate matter inhibits alveolar fluid reabsorption in mice via oxidant generation.
Mutlu GM, Snyder C, Bellmeyer A, Wang H, Hawkins K, Soberanes S, Welch LC, Ghio AJ, Chandel NS, Kamp D, Sznajder JI, Budinger GR
American journal of respiratory cell and molecular biology. 2006;34(6):670-6.
PMID: 16439801
Hypoxia-mediated degradation of Na,K-ATPase via mitochondrial reactive oxygen species and the ubiquitin-conjugating system.
Comellas AP, Dada LA, Lecuona E, Pesce LM, Chandel NS, Quesada N, Budinger GR, Strous GJ, Ciechanover A, Sznajder JI
Circulation research. 2006;98(10):1314-22.
PMID: 16614303
P53 mediates amosite asbestos-induced alveolar epithelial cell mitochondria-regulated apoptosis.
Panduri V, Surapureddi S, Soberanes S, Weitzman SA, Chandel N, Kamp DW
American journal of respiratory cell and molecular biology. 2006;34(4):443-52.
PMID: 16357363
Proapoptotic Bid is required for pulmonary fibrosis.
Budinger GR, Mutlu GM, Eisenbart J, Fuller AC, Bellmeyer AA, Baker CM, Wilson M, Ridge K, Barrett TA, Lee VY, Chandel NS
Proceedings of the National Academy of Sciences of the United States of America. 2006;103(12):4604-9.
PMID: 16537427
Intrinsic mechanism of estradiol-induced apoptosis in breast cancer cells resistant to estrogen deprivation.
Lewis JS, Meeke K, Osipo C, Ross EA, Kidawi N, Li T, Bell E, Chandel NS, Jordan VC
Journal of the National Cancer Institute. 2005 Dec;97(23):1746-59.
PMID: 16333030
Mitochondrial regulation of oxygen sensing.
Bell EL, Emerling BM, Chandel NS
Mitochondrion. 2005 Oct;5(5):322-32.
PMID: 16146708
Bleomycin induces alveolar epithelial cell death through JNK-dependent activation of the mitochondrial death pathway.
Lee VY, Schroedl C, Brunelle JK, Buccellato LJ, Akinci OI, Kaneto H, Snyder C, Eisenbart J, Budinger GR, Chandel NS
American journal of physiology. Lung cellular and molecular physiology. 2005 Oct;289(4):L521-8.
PMID: 16148050
Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling.
Emerling BM, Platanias LC, Black E, Nebreda AR, Davis RJ, Chandel NS
Molecular and cellular biology. 2005;25(12):4853-62.
PMID: 15923604
Oxygen sensing: getting pumped by sterols.
Emerling BM, Chandel NS
Science's STKE : signal transduction knowledge environment. 2005;2005(289):pe30.
PMID: 15972699
Active transforming growth factor-beta1 activates the procollagen I promoter in patients with acute lung injury.
Budinger GR, Chandel NS, Donnelly HK, Eisenbart J, Oberoi M, Jain M
Intensive care medicine. 2005;31(1):121-8.
PMID: 15565360
Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation.
Brunelle JK, Bell EL, Quesada NM, Vercauteren K, Tiranti V, Zeviani M, Scarpulla RC, Chandel NS
Cell metabolism. 2005;1(6):409-14.
PMID: 16054090
Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak.
Majewski N, Nogueira V, Bhaskar P, Coy PE, Skeen JE, Gottlob K, Chandel NS, Thompson CB, Robey RB, Hay N
Molecular cell. 2004 Dec;16(5):819-30.
PMID: 15574336
Mitochondrial-derived free radicals mediate asbestos-induced alveolar epithelial cell apoptosis.
Panduri V, Weitzman SA, Chandel NS, Kamp DW
American journal of physiology. Lung cellular and molecular physiology. 2004;286(6):L1220-7.
PMID: 14766669
Follicle-stimulating hormone activation of hypoxia-inducible factor-1 by the phosphatidylinositol 3-kinase/AKT/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is necessary for induction of select protein markers of follicular differentiation.
Alam H, Maizels ET, Park Y, Ghaey S, Feiger ZJ, Chandel NS, Hunzicker-Dunn M
The Journal of biological chemistry. 2004;279(19):19431-40.
PMID: 14982927
The alpha4 laminin subunit regulates endothelial cell survival.
DeHahn KC, Gonzales M, Gonzalez AM, Hopkinson SB, Chandel NS, Brunelle JK, Jones JC
Experimental cell research. 2004;294(1):281-9.
PMID: 14980521
Reactive oxygen species are required for hyperoxia-induced Bax activation and cell death in alveolar epithelial cells.
Buccellato LJ, Tso M, Akinci OI, Chandel NS, Budinger GR
The Journal of biological chemistry. 2004;279(8):6753-60.
PMID: 14625274
c-Myc sensitization to oxygen deprivation-induced cell death is dependent on Bax/Bak, but is independent of p53 and hypoxia-inducible factor-1.
Brunelle JK, Santore MT, Budinger GR, Tang Y, Barrett TA, Zong WX, Kandel E, Keith B, Simon MC, Thompson CB, Hay N, Chandel NS
The Journal of biological chemistry. 2004;279(6):4305-12.
PMID: 14627695
Angiostatin(4.5)-mediated apoptosis of vascular endothelial cells.
Hanford HA, Wong CA, Kassan H, Cundiff DL, Chandel N, Underwood S, Mitchell CA, Soff GA
Cancer research. 2003;63(14):4275-80.
PMID: 12874037
Hypoxia-induced endocytosis of Na,K-ATPase in alveolar epithelial cells is mediated by mitochondrial reactive oxygen species and PKC-zeta.
Dada LA, Chandel NS, Ridge KM, Pedemonte C, Bertorello AM, Sznajder JI
The Journal of clinical investigation. 2003;111(7):1057-64.
PMID: 12671055
The mitochondria-regulated death pathway mediates asbestos-induced alveolar epithelial cell apoptosis.
Panduri V, Weitzman SA, Chandel N, Kamp DW
American journal of respiratory cell and molecular biology. 2003;28(2):241-8.
PMID: 12540492
The panorama of the diversity of H5 subtype influenza viruses.
Ma HC, Chen JM, Chen JW, Sun YX, Li JM, Wang ZL
Virus genes. 2007;34(3):283-7.
PMID: 16924425
Alveolar fluid reabsorption is increased in rats with compensated heart failure.
Azzam ZS, Adir Y, Welch L, Chen J, Winaver J, Factor P, Krivoy N, Hoffman A, Sznajder JI, Abassi Z
American journal of physiology. Lung cellular and molecular physiology. 2006 Nov;291(5):L1094-100.
PMID: 16815890
A stable and differentiable RNA positive control for reverse transcription-polymerase chain reaction.
Chen JM, Guo LX, Sun CY, Sun YX, Chen JW, Li L, Wang ZL
Biotechnology letters. 2006 Nov;28(22):1787-92.
PMID: 16912918
Effect of cholesterol depletion on exocytosis of alveolar type II cells.
Chintagari NR, Jin N, Wang P, Narasaraju TA, Chen J, Liu L
American journal of respiratory cell and molecular biology. 2006;34(6):677-87.
PMID: 16439800
Alveolar type I cells protect rat lung epithelium from oxidative injury.
Chen J, Chen Z, Chintagari NR, Bhaskaran M, Jin N, Narasaraju T, Liu L
The Journal of physiology. 2006;572(Pt 3):625-38.
PMID: 16497717
Expression profile of IGF system during lung injury and recovery in rats exposed to hyperoxia: a possible role of IGF-1 in alveolar epithelial cell proliferation and differentiation.
Narasaraju TA, Chen H, Weng T, Bhaskaran M, Jin N, Chen J, Chen Z, Chinoy MR, Liu L
Journal of cellular biochemistry. 2006;97(5):984-98.
PMID: 16288470
Identification of rat lung--prominent genes by a parallel DNA microarray hybridization.
Chen Z, Chen J, Weng T, Jin N, Liu L
BMC genomics. 2006;7:47.
PMID: 16533406
A preliminary panorama of the diversity of N1 subtype influenza viruses.
Chen JM, Ma HC, Chen JW, Sun YX, Li JM, Wang ZL
Virus genes. 2006.
PMID: 17019634
Differential expression of GABAA receptor pi subunit in cultured rat alveolar epithelial cells.
Jin N, Narasaraju T, Kolliputi N, Chen J, Liu L
Cell and tissue research. 2005;321(2):173-83.
PMID: 15912403
Identification of two novel markers for alveolar epithelial type I and II cells.
Chen Z, Jin N, Narasaraju T, Chen J, McFarland LR, Scott M, Liu L
Biochemical and biophysical research communications. 2004;319(3):774-80.
PMID: 15184050
Isolation of highly pure alveolar epithelial type I and type II cells from rat lungs.
Chen J, Chen Z, Narasaraju T, Jin N, Liu L
Laboratory investigation; a journal of technical methods and pathology. 2004;84(6):727-35.
PMID: 15077123
E2A protein degradation by the ubiquitin-proteasome system is stage-dependent during muscle differentiation.
Sun L, Trausch-Azar JS, Ciechanover A, Schwartz AL
Oncogene. 2006.
PMID: 16909127
Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting.
Ciechanover A
Experimental biology and medicine (Maywood, N.J.). 2006;231(7):1197-211.
PMID: 16816126
Nobel round-table discussion #1: the future of interdisciplinary research and training.
Goodman SR, Ciechanover AJ, Hulse RA, Feng da H, Fluckiger S
Experimental biology and medicine (Maywood, N.J.). 2006;231(7):1225-39.
PMID: 16816128
Nobel round-table discussion #2: conflicts of interest, scientific misconduct, fair sharing, and intellectual property in an interdisciplinary/inter-institutional consortium.
Ehringhaus SH, Ciechanover AJ, Hulse RA, Pascal CB, Goodman SR
Experimental biology and medicine (Maywood, N.J.). 2006;231(7):1240-54.
PMID: 16816129
Two distinct ubiquitin-dependent mechanisms are involved in NF-kappaB p105 proteolysis.
Cohen S, Lahav-Baratz S, Ciechanover A
Biochemical and biophysical research communications. 2006;345(1):7-13.
PMID: 16678126
Hypoxia-mediated degradation of Na,K-ATPase via mitochondrial reactive oxygen species and the ubiquitin-conjugating system.
Comellas AP, Dada LA, Lecuona E, Pesce LM, Chandel NS, Quesada N, Budinger GR, Strous GJ, Ciechanover A, Sznajder JI
Circulation research. 2006;98(10):1314-22.
PMID: 16614303
The ubiquitin proteolytic system: from a vague idea, through basic mechanisms, and onto human diseases and drug targeting.
Ciechanover A
Neurology. 2006;66(2 Suppl 1):S7-19.
PMID: 16432150
The ubiquitin proteolytic system: from an idea to the patient bed.
Ciechanover A
Proceedings of the American Thoracic Society. 2006;3(1):21-31.
PMID: 16493148
The ubiquitin proteolytic system. From a vague idea, through basic mechanisms, and onto human diseases and drug targeting.
Ciechanover A
Neurology. 2005 Dec.
PMID: 16361379
Intracellular protein degradation: from a vague idea, through the lysosome and the ubiquitin-proteasome system, and onto human diseases and drug targeting (Nobel lecture).
Ciechanover A
Angewandte Chemie (International ed. in English). 2005;44(37):5944-67.
PMID: 16142822
Regulation of the proapoptotic ARTS protein by ubiquitin-mediated degradation.
Lotan R, Rotem A, Gonen H, Finberg JP, Kemeny S, Steller H, Ciechanover A, Larisch S
The Journal of biological chemistry. 2005;280(27):25802-10.
PMID: 15837787
Ubiquitin-proteasome-mediated degradation, intracellular localization, and protein synthesis of MyoD and Id1 during muscle differentiation.
Sun L, Trausch-Azar JS, Ciechanover A, Schwartz AL
The Journal of biological chemistry. 2005;280(28):26448-56.
PMID: 15888449
Proteolysis: from the lysosome to ubiquitin and the proteasome.
Ciechanover A
Nature reviews. Molecular cell biology. 2005;6(1):79-87.
PMID: 15688069
N-terminal ubiquitination.
Ciechanover A
Methods in molecular biology (Clifton, N.J.). 2005;301:255-70.
PMID: 15917637
E12 and E47 modulate cellular localization and proteasome-mediated degradation of MyoD and Id1.
Lingbeck JM, Trausch-Azar JS, Ciechanover A, Schwartz AL
Oncogene. 2005;24(42):6376-84.
PMID: 16007194
The ubiquitin-proteasome system--micro target for macro intervention?
Herrmann J, Ciechanover A, Lerman LO, Lerman A
International journal of cardiovascular interventions. 2005;7(1):5-13.
PMID: 16019609
Early work on the ubiquitin proteasome system, an interview with Aaron Ciechanover. Interview by CDD.
Ciechanover A
Cell death and differentiation. 2005;12(9):1167-77.
PMID: 16094393
Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting.
Ciechanover A
Cell death and differentiation. 2005;12(9):1178-90.
PMID: 16094394
Hypoxia-mediated degradation of Na,K-ATPase via mitochondrial reactive oxygen species and the ubiquitin-conjugating system.
Comellas AP, Dada LA, Lecuona E, Pesce LM, Chandel NS, Quesada N, Budinger GR, Strous GJ, Ciechanover A, Sznajder JI
Circulation research. 2006;98(10):1314-22.
PMID: 16614303
Norepinephrine increases alveolar fluid reabsorption and Na,K-ATPase activity.
Azzam ZS, Adir Y, Crespo A, Comellas A, Lecuona E, Dada LA, Krivoy N, Rutschman DH, Sznajder JI, Ridge KM
American journal of respiratory and critical care medicine. 2004 Oct;170(7):730-6.
PMID: 15256395
Cortisol levels and mortality in severe sepsis.
Sam S, Corbridge TC, Mokhlesi B, Comellas AP, Molitch ME
Clinical endocrinology. 2004;60(1):29-35.
PMID: 14678284
Beta-adrenergic agonists regulate Na-K-ATPase via p70S6k.
Pesce L, Comellas A, Sznajder JI
American journal of physiology. Lung cellular and molecular physiology. 2003 Oct;285(4):L802-7.
PMID: 12704019
Fibroblast growth factor-10 upregulates Na,K-ATPase via the MAPK pathway.
Upadhyay D, Lecuona E, Comellas A, Kamp DW, Sznajder JI
FEBS letters. 2003;545(2-3):173-6.
PMID: 12804770
Scorpion venom decreases lung liquid clearance in rats.
Comellas AP, Pesce LM, Azzam Z, Saldias FJ, Sznajder JI
American journal of respiratory and critical care medicine. 2003;167(8):1064-7.
PMID: 12684245
Autologous non-myeloablative hematopoietic stem cell transplantation in patients with systemic sclerosis.
Oyama Y, Barr WG, Statkute L, Corbridge T, Gonda EA, Jovanovic B, Testori A, Burt RK
Bone marrow transplantation. 2007.
PMID: 17646844
Multiple cysts in the kidney and lungs in a patient with polycystic kidney disease and lymphangioleiomyomatosis.
Lam AP, Corbridge TC
TheScientificWorldJournal. 2007;7:80-2.
PMID: 17334601
Prevalence and reversibility of pulmonary dysfunction in refractory systemic lupus: improvement correlates with disease remission following hematopoietic stem cell transplantation.
Traynor AE, Corbridge TC, Eagan AE, Barr WG, Liu Q, Oyama Y, Burt RK
Chest. 2005;127(5):1680-9.
PMID: 15888846
Severe exacerbations of asthma.
Corbridge SJ, Corbridge TC
Critical care nursing quarterly. 2004;27(3):207-28; quiz 229-30.
PMID: 15291048
Asthma--Part I.
Corbridge SJ, Corbridge TC, Richlin D
AAOHN journal : official journal of the American Association of Occupational Health Nurses. 2003;51(8):331-2.
PMID: 12934858
Adult toxicology in critical care: Part II: specific poisonings.
Mokhlesi B, Leikin JB, Murray P, Corbridge TC
Chest. 2003;123(3):897-922.
PMID: 12628894
Adult toxicology in critical care: part I: general approach to the intoxicated patient.
Mokhlesi B, Leiken JB, Murray P, Corbridge TC
Chest. 2003;123(2):577-92.
PMID: 12576382
Asbestos and the pleura: a review.
Cugell DW, Kamp DW
Chest. 2004;125(3):1103-17.
PMID: 15006974
Phosphorylation of adaptor protein-2 mu2 is essential for Na+,K+-ATPase endocytosis in response to either G protein-coupled receptor or reactive oxygen species.
Chen Z, Krmar RT, Dada L, Efendiev R, Leibiger IB, Pedemonte CH, Katz AI, Sznajder JI, Bertorello AM
American journal of respiratory cell and molecular biology. 2006;35(1):127-32.
PMID: 16498080
Hypoxia-mediated degradation of Na,K-ATPase via mitochondrial reactive oxygen species and the ubiquitin-conjugating system.
Comellas AP, Dada LA, Lecuona E, Pesce LM, Chandel NS, Quesada N, Budinger GR, Strous GJ, Ciechanover A, Sznajder JI
Circulation research. 2006;98(10):1314-22.
PMID: 16614303
Norepinephrine increases alveolar fluid reabsorption and Na,K-ATPase activity.
Azzam ZS, Adir Y, Crespo A, Comellas A, Lecuona E, Dada LA, Krivoy N, Rutschman DH, Sznajder JI, Ridge KM
American journal of respiratory and critical care medicine. 2004 Oct;170(7):730-6.
PMID: 15256395
Hypoxia-induced endocytosis of Na,K-ATPase in alveolar epithelial cells is mediated by mitochondrial reactive oxygen species and PKC-zeta.
Dada LA, Chandel NS, Ridge KM, Pedemonte C, Bertorello AM, Sznajder JI
The Journal of clinical investigation. 2003;111(7):1057-64.
PMID: 12671055
Mechanisms of pulmonary edema clearance during acute hypoxemic respiratory failure: role of the Na,K-ATPase.
Dada LA, Sznajder JI
Critical care medicine. 2003;31(4 Suppl):S248-52.
PMID: 12682448
Electroporation-mediated Gene Transfer of the Na+,K+-ATPase Rescues Endotoxin-induced Lung Injury.
Mutlu GM, Machado-Aranda D, Norton JE, Bellmeyer A, Urich D, Zhou R, Dean DA
American journal of respiratory and critical care medicine. 2007.
PMID: 17556717
Gene transfer of interleukin 10 to the murine cornea using electroporation.
Zhou R, Dean DA
Experimental biology and medicine (Maywood, N.J.). 2007;232(3):362-9.
PMID: 17327469
Electroporation-mediated transfer of plasmids to the lung results in reduced TLR9 signaling and inflammation.
Zhou R, Norton JE, Zhang N, Dean DA
Gene therapy. 2007.
PMID: 17344904
Intracellular trafficking of plasmids for gene therapy: mechanisms of cytoplasmic movement and nuclear import.
Vaughan EE, DeGiulio JV, Dean DA
Current gene therapy. 2006 Dec;6(6):671-81.
PMID: 17168698
Leptin Resistance Protects Mice from Hyperoxia-Induced Acute Lung Injury.
Bellmeyer A, Martino JM, Chandel NS, Budinger GS, Dean DA, Mutlu GM
American journal of respiratory and critical care medicine. 2006 Dec.
PMID: 17185651
Pol I Transcription and Pre-rRNA Processing Are Coordinated in a Transcription-dependent Manner in Mammalian Cells.
Kopp K, Gasiorowski JZ, Chen D, Gilmore R, Norton JT, Wang C, Leary DJ, Chan EK, Dean DA, Huang S
Molecular biology of the cell. 2006 Nov.
PMID: 17108330
Nondisruptive, sequence-specific coupling of fluorochromes to plasmid DNA.
Hillery E, Munkonge FM, Xenariou S, Dean DA, Alton EW
Analytical biochemistry. 2006;352(2):169-75.
PMID: 16579951
Cyclic stretch-induced reorganization of the cytoskeleton and its role in enhanced gene transfer.
Geiger RC, Taylor W, Glucksberg MR, Dean DA
Gene therapy. 2006;13(8):725-31.
PMID: 16437132
Intracellular trafficking of plasmids during transfection is mediated by microtubules.
Vaughan EE, Dean DA
Molecular therapy : the journal of the American Society of Gene Therapy. 2006;13(2):422-8.
PMID: 16301002
Postmitotic nuclear retention of episomal plasmids is altered by DNA labeling and detection methods.
Gasiorowski JZ, Dean DA
Molecular therapy : the journal of the American Society of Gene Therapy. 2005;12(3):460-7.
PMID: 15978873
Nuclear entry of nonviral vectors.
Dean DA, Strong DD, Zimmer WE
Gene therapy. 2005;12(11):881-90.
PMID: 15908994
Laminin-6 assembles into multimolecular fibrillar complexes with perlecan and participates in mechanical-signal transduction via a dystroglycan-dependent, integrin-independent mechanism.
Jones JC, Lane K, Hopkinson SB, Lecuona E, Geiger RC, Dean DA, Correa-Meyer E, Gonzales M, Campbell K, Sznajder JI, Budinger S
Journal of cell science. 2005;118(Pt 12):2557-66.
PMID: 15928048
Gene transfer of the Na+,K+-ATPase beta1 subunit using electroporation increases lung liquid clearance.
Machado-Aranda D, Adir Y, Young JL, Briva A, Budinger GR, Yeldandi AV, Sznajder JI, Dean DA
American journal of respiratory and critical care medicine. 2005;171(3):204-11.
PMID: 15516538
Effect of vinblastine on transfection: influence of cell types, cationic lipids and promoters.
Wang L, Dean DA, Macdonald RC
Current drug delivery. 2005;2(1):93-6.
PMID: 16305411
Nonviral gene transfer to skeletal, smooth, and cardiac muscle in living animals.
Dean DA
American journal of physiology. Cell physiology. 2005;289(2):C233-45.
PMID: 16002623
Intracellular trafficking of nucleic acids.
Zhou R, Geiger RC, Dean DA
Expert opinion on drug delivery. 2004 Nov;1(1):127-40.
PMID: 16296725
Hydroporation as the mechanism of hydrodynamic delivery.
Zhang G, Gao X, Song YK, Vollmer R, Stolz DB, Gasiorowski JZ, Dean DA, Liu D
Gene therapy. 2004;11(8):675-82.
PMID: 14724673
Electroporation of the vasculature and the lung.
Dean DA
DNA and cell biology. 2003 Dec;22(12):797-806.
PMID: 14683590
Electroporation-mediated delivery of catalytic oligodeoxynucleotides for manipulation of vascular gene expression.
Nunamaker EA, Zhang HY, Shirasawa Y, Benoit JN, Dean DA
American journal of physiology. Heart and circulatory physiology. 2003 Nov;285(5):H2240-7.
PMID: 12881213
Electroporation as a method for high-level nonviral gene transfer to the lung.
Dean DA, Machado-Aranda D, Blair-Parks K, Yeldandi AV, Young JL
Gene therapy. 2003;10(18):1608-15.
PMID: 12907953
Effect of a DNA nuclear targeting sequence on gene transfer and expression of plasmids in the intact vasculature.
Young JL, Benoit JN, Dean DA
Gene therapy. 2003;10(17):1465-70.
PMID: 12900761
Nuclear transport: an emerging opportunity for drug targeting.
Dean DA
Advanced drug delivery reviews. 2003;55(6):699-702.
PMID: 12788534
Mechanisms of nuclear transport and interventions.
Gasiorowski JZ, Dean DA
Advanced drug delivery reviews. 2003;55(6):703-16.
PMID: 12788535
Emerging significance of plasmid DNA nuclear import in gene therapy.
Munkonge FM, Dean DA, Hillery E, Griesenbach U, Alton EW
Advanced drug delivery reviews. 2003;55(6):749-60.
PMID: 12788538
Modulation of protein kinase C (PKC)-mediated contraction and the possible role of PKC epsilon in rat mesenteric arteries.
Shirasawa Y, Rutland TJ, Young JL, Dean DA, Joseph BN
Frontiers in bioscience : a journal and virtual library. 2003;8:a133-8.
PMID: 12700091
The effects of cyclic stretch on gene transfer in alveolar epithelial cells.
Taylor W, Gokay KE, Capaccio C, Davis E, Glucksberg M, Dean DA
Molecular therapy : the journal of the American Society of Gene Therapy. 2003;7(4):542-9.
PMID: 12727118
Risk assessment for inpatient survival in the long-term acute care setting after prolonged critical illness.
Dematte D'Amico JE, Donnelly HK, Mutlu GM, Feinglass J, Jovanovic BD, Ndukwu IM
Chest. 2003;124(3):1039-45.
PMID: 12970035
Airborne particulate matter inhibits alveolar fluid reabsorption in mice via oxidant generation.
Mutlu GM, Snyder C, Bellmeyer A, Wang H, Hawkins K, Soberanes S, Welch LC, Ghio AJ, Chandel NS, Kamp D, Sznajder JI, Budinger GR
American journal of respiratory cell and molecular biology. 2006;34(6):670-6.
PMID: 16439801
The intrinsic apoptotic pathway is required for lipopolysaccharide-induced lung endothelial cell death.
Wang HL, Akinci IO, Baker CM, Urich D, Bellmeyer A, Jain M, Chandel NS, Mutlu GM, Budinger GR
Journal of immunology (Baltimore, Md. : 1950). 2007;179(3):1834-41.
PMID: 17641050
Mycophenolate mofetil: a promising novel therapy in systemic sclerosis.
Jain M, Varga J
Current rheumatology reports. 2007;9(2):133-5.
PMID: 17502043
A 48-year-old woman with skin lesions, renal masses, and spontaneous pneumothorax.
Kalhan R, Yeldandi AV, Jain M
Chest. 2007;131(2):624-7.
PMID: 17296671
Bench-to-bedside review: Distal airways in acute respiratory distress syndrome.
Jain M, Sznajder JI
Critical care (London, England). 2007;11(1):206.
PMID: 17306039
Bronchoalveolar lavage fluid from patients with acute lung injury/acute respiratory distress syndrome induces myofibroblast differentiation.
Synenki L, Chandel NS, Budinger GR, Donnelly HK, Topin J, Eisenbart J, Jovanovic B, Jain M
Critical care medicine. 2007.
PMID: 17255860
Bosentan for the treatment of systemic sclerosis-associated pulmonary arterial hypertension, pulmonary fibrosis and digital ulcers.
Jain M, Varga J
Expert opinion on pharmacotherapy. 2006;7(11):1487-501.
PMID: 16859432
Cystic fibrosis patients have poor sleep quality despite normal sleep latency and efficiency.
Jankelowitz L, Reid KJ, Wolfe L, Cullina J, Zee PC, Jain M
Chest. 2005;127(5):1593-9.
PMID: 15888833
Active transforming growth factor-beta1 activates the procollagen I promoter in patients with acute lung injury.
Budinger GR, Chandel NS, Donnelly HK, Eisenbart J, Oberoi M, Jain M
Intensive care medicine. 2005;31(1):121-8.
PMID: 15565360
Low tidal volume needs to be used in patients with acute respiratory distress syndrome.
Jain M, Sznajder JI
Critical care medicine. 2005;33(1):239-40.
PMID: 15644681
Effects of hypoxia on the alveolar epithelium.
Jain M, Sznajder JI
Proceedings of the American Thoracic Society. 2005;2(3):202-5.
PMID: 16222038
Type III secretion phenotypes of Pseudomonas aeruginosa strains change during infection of individuals with cystic fibrosis.
Jain M, Ramirez D, Seshadri R, Cullina JF, Powers CA, Schulert GS, Bar-Meir M, Sullivan CL, McColley SA, Hauser AR
Journal of clinical microbiology. 2004 Nov;42(11):5229-37.
PMID: 15528719
Emphysematous cystitis and renal stones in cystic fibrosis.
Upadhyay D, Jain M
JAMA : the journal of the American Medical Association. 2004 Oct;292(16):1953-4.
PMID: 15507579
Variability in interventions with pulmonary artery catheter data.
Jain M, Canham M, Upadhyay D, Corbridge T
Intensive care medicine. 2003 Nov;29(11):2059-62.
PMID: 14669763
Potential reasons why physicians underuse lung-protective ventilation: a retrospective cohort study using physician documentation.
Mikkelsen ME, Dedhiya PM, Kalhan R, Gallop RJ, Lanken PN, Fuchs BD
Respiratory care. 2008;53(4):455-61.
PMID: 18364057
A 23-year-old woman with sudden-onset dyspnea and chest pain penetrating to the back.
Kwon JS, Blum MG, Kalhan R
Chest. 2008;133(2):574-8.
PMID: 18252926
A 48-year-old woman with skin lesions, renal masses, and spontaneous pneumothorax.
Kalhan R, Yeldandi AV, Jain M
Chest. 2007;131(2):624-7.
PMID: 17296671
A mechanism of benefit of soy genistein in asthma: inhibition of eosinophil p38-dependent leukotriene synthesis.
Kalhan R, Smith LJ, Nlend MC, Nair A, Hixon JL, Sporn PH
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2007.
PMID: 17979994
Underuse of lung protective ventilation: analysis of potential factors to explain physician behavior.
Kalhan R, Mikkelsen M, Dedhiya P, Christie J, Gaughan C, Lanken PN, Finkel B, Gallop R, Fuchs BD
Critical care medicine. 2006;34(2):300-6.
PMID: 16424706
Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway.
Mutlu GM, Green D, Bellmeyer A, Baker CM, Burgess Z, Rajamannan N, Christman JW, Foiles N, Kamp DW, Ghio AJ, Chandel NS, Dean DA, Sznajder JI, Budinger GR
The Journal of clinical investigation. 2007.
PMID: 17885684
p53 mediates particulate matter-induced alveolar epithelial cell mitochondria-regulated apoptosis.
Soberanes S, Panduri V, Mutlu GM, Ghio A, Bundinger GR, Kamp DW
American journal of respiratory and critical care medicine. 2006 Dec;174(11):1229-38.
PMID: 16946128
Airborne particulate matter inhibits alveolar fluid reabsorption in mice via oxidant generation.
Mutlu GM, Snyder C, Bellmeyer A, Wang H, Hawkins K, Soberanes S, Welch LC, Ghio AJ, Chandel NS, Kamp D, Sznajder JI, Budinger GR
American journal of respiratory cell and molecular biology. 2006;34(6):670-6.
PMID: 16439801
P53 mediates amosite asbestos-induced alveolar epithelial cell mitochondria-regulated apoptosis.
Panduri V, Surapureddi S, Soberanes S, Weitzman SA, Chandel N, Kamp DW
American journal of respiratory cell and molecular biology. 2006;34(4):443-52.
PMID: 16357363
KGF prevents oxygen-mediated damage in ARPE-19 cells.
Geiger RC, Waters CM, Kamp DW, Glucksberg MR
Investigative ophthalmology & visual science. 2005;46(9):3435-42.
PMID: 16123449
Fibroblast growth factor-10 prevents asbestos-induced alveolar epithelial cell apoptosis by a mitogen-activated protein kinase-dependent mechanism.
Upadhyay D, Panduri V, Kamp DW
American journal of respiratory cell and molecular biology. 2005;32(3):232-8.
PMID: 15618436
Radiographic opacities.
Mann H
Chest. 2004 Oct;126(4):1388; author reply 1388..
PMID: 15486417
Fibroblast growth factor-10 attenuates H2O2-induced alveolar epithelial cell DNA damage: role of MAPK activation and DNA repair.
Upadhyay D, Bundesmann M, Panduri V, Correa-Meyer E, Kamp DW
American journal of respiratory cell and molecular biology. 2004;31(1):107-13.
PMID: 14975937
Mitochondrial-derived free radicals mediate asbestos-induced alveolar epithelial cell apoptosis.
Panduri V, Weitzman SA, Chandel NS, Kamp DW
American journal of physiology. Lung cellular and molecular physiology. 2004;286(6):L1220-7.
PMID: 14766669
Asbestos-related pulmonary diseases.
Corbridge SJ, Kamp DW
AAOHN journal : official journal of the American Association of Occupational Health Nurses. 2004;52(2):49-51.
PMID: 14979614
Asbestos and the pleura: a review.
Cugell DW, Kamp DW
Chest. 2004;125(3):1103-17.
PMID: 15006974
Idiopathic pulmonary fibrosis: the inflammation hypothesis revisited.
Kamp DW
Chest. 2003 Oct;124(4):1187-90.
PMID: 14555542
Particulate matter induces alveolar epithelial cell DNA damage and apoptosis: role of free radicals and the mitochondria.
Upadhyay D, Panduri V, Ghio A, Kamp DW
American journal of respiratory cell and molecular biology. 2003;29(2):180-7.
PMID: 12600817
Asbestos-induced pulmonary toxicity: role of DNA damage and apoptosis.
Upadhyay D, Kamp DW
Experimental biology and medicine (Maywood, N.J.). 2003;228(6):650-9.
PMID: 12773695
Fibroblast growth factor-10 upregulates Na,K-ATPase via the MAPK pathway.
Upadhyay D, Lecuona E, Comellas A, Kamp DW, Sznajder JI
FEBS letters. 2003;545(2-3):173-6.
PMID: 12804770
Multiple roles of oxidants in the pathogenesis of asbestos-induced diseases.
Shukla A, Gulumian M, Hei TK, Kamp D, Rahman Q, Mossman BT
Free radical biology & medicine. 2003;34(9):1117-29.
PMID: 12706492
FGF-10 prevents mechanical stretch-induced alveolar epithelial cell DNA damage via MAPK activation.
Upadhyay D, Correa-Meyer E, Sznajder JI, Kamp DW
American journal of physiology. Lung cellular and molecular physiology. 2003;284(2):L350-9.
PMID: 12533312
The mitochondria-regulated death pathway mediates asbestos-induced alveolar epithelial cell apoptosis.
Panduri V, Weitzman SA, Chandel N, Kamp DW
American journal of respiratory cell and molecular biology. 2003;28(2):241-8.
PMID: 12540492
Methicillin-Resistant S. aureus Ventilator-Associated Pneumonia: Strategies to Prevent and Treat.
Lam AP, Wunderink RG
Seminars in respiratory and critical care medicine. 2006;27(1):92-103.
PMID: 16508885
AMP-activated protein kinase regulates CO(2)-induced alveolar epithelial dysfunction in rats and human cells by promoting Na,K-ATPase endocytosis.
Vadász I, Dada LA, Briva A, Trejo HE, Welch LC, Chen J, Tóth PT, Lecuona E, Witters LA, Schumacker PT, Chandel NS, Seeger W, Sznajder JI
The Journal of clinical investigation. 2008;118(2):752-762.
PMID: 18188452
Hypoxia-mediated Na-K-ATPase degradation requires von Hippel Lindau protein.
Zhou G, Dada LA, Chandel NS, Iwai K, Lecuona E, Ciechanover A, Sznajder JI
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2007 Dec.
PMID: 18073334
High CO(2) Levels Impair Alveolar Epithelial Function Independently of pH.
Briva A, Vadász I, Lecuona E, Welch LC, Chen J, Dada LA, Trejo HE, Dumasius V, Azzam ZS, Myrianthefs PM, Batlle D, Gruenbaum Y, Sznajder JI
PLoS ONE. 2007 Nov;2(11):e1238.
PMID: 18043745
Carbonic Anhydrase II and Alveolar Fluid Reabsorption During Hypercapnia.
Chen J, Lecuona E, Briva A, Welch LC, Sznajder JI
American journal of respiratory cell and molecular biology. 2007.
PMID: 17690328
Role of the small GTPase RhoA in the hypoxia-induced decrease of plasma membrane Na,K-ATPase in A549 cells.
Dada LA, Novoa E, Lecuona E, Sun H, Sznajder JI
Journal of cell science. 2007.
PMID: 17550967
Regulation of Na,K-ATPase during acute lung injury.
Lecuona E, Trejo HE, Sznajder JI
Journal of bioenergetics and biomembranes. 2007.
PMID: 17972021
Hypoxia-mediated degradation of Na,K-ATPase via mitochondrial reactive oxygen species and the ubiquitin-conjugating system.
Comellas AP, Dada LA, Lecuona E, Pesce LM, Chandel NS, Quesada N, Budinger GR, Strous GJ, Ciechanover A, Sznajder JI
Circulation research. 2006;98(10):1314-22.
PMID: 16614303
Na,K-ATPase alpha1-subunit dephosphorylation by protein phosphatase 2A is necessary for its recruitment to the plasma membrane.
Lecuona E, Dada LA, Sun H, Butti ML, Zhou G, Chew TL, Sznajder JI
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2006;20(14):2618-20.
PMID: 17065225
Hypocapnic but not metabolic alkalosis impairs alveolar fluid reabsorption.
Myrianthefs PM, Briva A, Lecuona E, Dumasius V, Rutschman DH, Ridge KM, Baltopoulos GJ, Sznajder JI
American journal of respiratory and critical care medicine. 2005;171(11):1267-71.
PMID: 15764729
Laminin-6 assembles into multimolecular fibrillar complexes with perlecan and participates in mechanical-signal transduction via a dystroglycan-dependent, integrin-independent mechanism.
Jones JC, Lane K, Hopkinson SB, Lecuona E, Geiger RC, Dean DA, Correa-Meyer E, Gonzales M, Campbell K, Sznajder JI, Budinger S
Journal of cell science. 2005;118(Pt 12):2557-66.
PMID: 15928048
Norepinephrine increases alveolar fluid reabsorption and Na,K-ATPase activity.
Azzam ZS, Adir Y, Crespo A, Comellas A, Lecuona E, Dada LA, Krivoy N, Rutschman DH, Sznajder JI, Ridge KM
American journal of respiratory and critical care medicine. 2004 Oct;170(7):730-6.
PMID: 15256395
Augmentation of endogenous dopamine production increases lung liquid clearance.
Adir Y, Azzam ZS, Lecuona E, Leal S, Pesce L, Dumasius V, Bertorello AM, Factor P, Young JB, Ridge KM, Sznajder JI
American journal of respiratory and critical care medicine. 2004;169(6):757-63.
PMID: 14701706
The GTP-binding protein RhoA mediates Na,K-ATPase exocytosis in alveolar epithelial cells.
Lecuona E, Ridge K, Pesce L, Batlle D, Sznajder JI
Molecular biology of the cell. 2003;14(9):3888-97.
PMID: 12972572
Fibroblast growth factor-10 upregulates Na,K-ATPase via the MAPK pathway.
Upadhyay D, Lecuona E, Comellas A, Kamp DW, Sznajder JI
FEBS letters. 2003;545(2-3):173-6.
PMID: 12804770
Rho kinase inhibition initiates apoptosis in human airway epithelial cells.
Moore M, Marroquin BA, Gugliotta W, Tse R, White SR
American journal of respiratory cell and molecular biology. 2004;30(3):379-87.
PMID: 12933355
The Reply.
Mutlu GM, Bellmeyer A, Mutlu EA, Rubinstein I
The American journal of medicine. 2007 Dec;120(12):e23.
PMID: 18060908
The intrinsic apoptotic pathway is required for lipopolysaccharide-induced lung endothelial cell death.
Wang HL, Akinci IO, Baker CM, Urich D, Bellmeyer A, Jain M, Chandel NS, Mutlu GM, Budinger GR
Journal of immunology (Baltimore, Md. : 1950). 2007;179(3):1834-41.
PMID: 17641050
Alveolar Epithelial {beta}2-Adrenergic Receptors.
Mutlu GM, Factor P
American journal of respiratory cell and molecular biology. 2007.
PMID: 17709598
Electroporation-mediated Gene Transfer of the Na+,K+-ATPase Rescues Endotoxin-induced Lung Injury.
Mutlu GM, Machado-Aranda D, Norton JE, Bellmeyer A, Urich D, Zhou R, Dean DA
American journal of respiratory and critical care medicine. 2007.
PMID: 17556717
Adenosine regulation of alveolar fluid clearance.
Factor P, Mutlu GM, Chen L, Mohameed J, Akhmedov AT, Meng FJ, Jilling T, Lewis ER, Johnson MD, Xu A, Kass D, Martino JM, Bellmeyer A, Albazi JS, Emala C, Lee HT, Dobbs LG, Matalon S
Proceedings of the National Academy of Sciences of the United States of America. 2007;104(10):4083-8.
PMID: 17360481
Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway.
Mutlu GM, Green D, Bellmeyer A, Baker CM, Burgess Z, Rajamannan N, Christman JW, Foiles N, Kamp DW, Ghio AJ, Chandel NS, Dean DA, Sznajder JI, Budinger GR
The Journal of clinical investigation. 2007.
PMID: 17885684
p53 mediates particulate matter-induced alveolar epithelial cell mitochondria-regulated apoptosis.
Soberanes S, Panduri V, Mutlu GM, Ghio A, Bundinger GR, Kamp DW
American journal of respiratory and critical care medicine. 2006 Dec;174(11):1229-38.
PMID: 16946128
Predictors of acute lung injury and severe hypoxemia in patients undergoing operative talc pleurodesis.
Kuzniar TJ, Blum MG, Kasibowska-Kuzniar K, Mutlu GM
The Annals of thoracic surgery. 2006 Dec;82(6):1976-81.
PMID: 17126094
Leptin Resistance Protects Mice from Hyperoxia-Induced Acute Lung Injury.
Bellmeyer A, Martino JM, Chandel NS, Budinger GS, Dean DA, Mutlu GM
American journal of respiratory and critical care medicine. 2006 Dec.
PMID: 17185651
Severe pseudomonal infections.
Mutlu GM, Wunderink RG
Current opinion in critical care. 2006 Oct;12(5):458-63.
PMID: 16943726
Air pollution impairs lung's ability to clear edema fluid.
Mutlu GM, Bellmeyer A, Budinger GR
The American journal of cardiology. 2006;98(3):423-4.
PMID: 16860038
Pulmonary adverse events of anti-tumor necrosis factor-alpha antibody therapy.
Mutlu GM, Mutlu EA, Bellmeyer A, Rubinstein I
The American journal of medicine. 2006;119(8):639-46.
PMID: 16887405
Clinical manifestations of sarcoidosis among inner-city African-American dwellers.
Mutlu GM, Rubinstein I
Journal of the National Medical Association. 2006;98(7):1140-3.
PMID: 16895285
Airborne particulate matter inhibits alveolar fluid reabsorption in mice via oxidant generation.
Mutlu GM, Snyder C, Bellmeyer A, Wang H, Hawkins K, Soberanes S, Welch LC, Ghio AJ, Chandel NS, Kamp D, Sznajder JI, Budinger GR
American journal of respiratory cell and molecular biology. 2006;34(6):670-6.
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